HomeCU DenverCollege of Liberal Arts & ScienceCLAS LabsDepartment of Integrative Biology

Publications

Meredith G, D’Ippolito A, Zeidner LC, Hostetter L, Faulds K, Arnold TH, Popkie AP, Doble BW, Marnellos G, Adams C, Wang Y, and Phiel CJ (2015) Glycogen Synthase Kinase-3 (Gsk-3) Plays a Fundamental Role In Maintaining DNA Methylation At Imprinted Loci In Mouse Embryonic Stem Cells, Molecular Biology of the Cell 26(11): 2139-2150, PMID: 25833708.

Battacherjee R, Dudki T, Goswami S, Popkie A, Phiel CJ, Kline D, and Vijayaraghavan S (2015) Targeted disruption of GSK-3α affects sperm motility resulting in male infertility, Biology of Reproduction 92:1-12, PMID: 25568307.

Bartman CM, Egelston J, Ren X, Das R, and Phiel CJ (2015) A Simple and Efficient Method for Transfecting Mouse Embryonic Stem Cells Using Polyethylenimine, Experimental Cell Research 330: 178-185, PMID: 25102378.

Zhen CY, Duc, HN, Kokotovic M, Phiel CJ, and Ren X (2014) Immobilization of PRC1 Complex at Mitotic Chromosomes by Cbx2 in a PRC2-Independent Mechanism, Molecular Biology of the Cell 25(23):3726-3739, PMID: 25232004.

Bartman CM, Egelston J, Zeidner LC, D’Ippolito, A, Kattula S, Doble BW, and Phiel CJ (2014) Gene expression profiling in mouse embryonic stem cells reveals glycogen synthase kinase-3-dependent targets of phosphatidylinositol 3-kinase and Wnt/β-catenin signaling pathways, Frontiers in Endocrinology 5:133, PMID: 25165462.

Phiel CJ, Wilson CA, Lee VM-Y and Klein PS (2011) Reply to GSK-3α/β kinases and amyloid production in vivo, Nature 480:E6, PMID: 22158251.

Zeidner LC, Buescher JL, and Phiel CJ (2011) A Novel Interaction Between Glycogen Synthase Kinase-3α (GSK-3α) and the Scaffold Protein Receptor for Activated C-Kinase 1 (RACK1) Regulates the Circadian Clock, International Journal of Biochemistry and Molecular Biology 2(4):318-327, PMID: 22187666.

Fleming JL, Phiel CJ, and Toland AE (2011) The Role for Oxidative Stress in Aberrant DNA Methylation in Alzheimer’s Disease, Current Alzheimer Research 9(9):1077-1096, PMID: 21605062.

Popkie AP, Zeidner LC, Albrecht AM, D’Ippolito A, Eckardt S, Newsom DE, Groden J, Doble BW, Aronow B, McLaughlin KJ, White P, Phiel CJ (2010) Phosphatidylinositol 3-Kinase (PI3K) Signaling via Glycogen Synthase Kinase-3 (Gsk-3) Regulates DNA Methylation of Imprinted Loci., Journal of Biological Chemistry 285(53):41337-47, PMID: 21047779.

He F, Popkie AP, Xiong W, Li L, Wang Y, Phiel CJ, Chen Y. (2010) Gsk3β is required in the epithelium for palatal elevation in mice., Developmental Dynamics 239(12):3235-46, PMID: 20981831.

Yang J, Phiel CJ. (2010) Functions of B56-containing PP2As in major developmental and cancer signaling pathways., Life Sciences 87(23-26):659-66. Review, PMID: 20934435.

Buescher JL and Phiel CJ (2010) A non-catalytic domain of glycogen synthase kinase-3 (GSK-3) is essential for activity,Journal of Biological Chemistry 285:7957-7963, PMID: 20080974.

Rorick AM, Mei W, Liette NL, Phiel C, El-Hodiri HM, Yang J. (2007) PP2A:B56epsilon is required for eye induction and eye field separation., Developmental Biology 302(2):477-93, PMID: 17074314.

Checler F, Alves da Costa C, Ayral E, Andrau D, Dumanchin C, Farzan M, Hernandez JF, Martinez J, Lefranc-Jullien S, Marambaud P, Pasini A, Petit A, Phiel CJ, Robert P, St. George-Hyslop P and Wilk S (2005) JLK inhibitors: Isocoumarin compounds as putative probes to selectively target the γ-secretase pathway, Current Alzheimer Research 2:327-334, PMID: 15974898.

Phiel CJ, Wilson CA, Lee VM-Y and Klein PS (2003) GSK-3α Regulates Production of Alzheimer’s Disease Amyloid-β Peptides, Nature 423:435-439, PMID: 12761548.

Zhang F, Phiel CJ, Spece L, Gurvich N and Klein PS (2003) Inhibitory phosphorylation of Glycogen Synthase Kinase-3 (GSK-3) in Response to Lithium: Evidence for Autoregulation of GSK-3, Journal of Biological Chemistry 278:33067-33077, PMID: 12796505.

Checler F, Pasini A, Alves da Costa C, Ayral E, Hernandez JF, Dumanchin-Njock C, Phiel CJ, Marambaud P, Wilk S, Farzan M, Boisbrun M, Fulcrand P, Martinez J, Andrau D, and Petit A (2003) JLK isocoumarin inhibitors: Selective γ-secretase inhibitors that do not interfere with Notch pathway in vitro or in vivo, Journal of Neuroscience Research 74:370-377, PMID: 14598313.

Gabetta V, Trzyna WT, Phiel CJ and McHugh KM (2003) Vesicle-Associated Protein-A is Differentially Expressed During Intestinal Smooth Muscle Cell Differentiation, Developmental Dynamics 228:11-20, PMID: 12950075.

Phiel CJ, Zhang F, Huang EY, Guenther MG, Lazar MA and Klein PS (2001) Histone Deacetylase is a Direct Target of Valproic Acid, a Potent Anticonvulsant, Mood Stabilizer, and Teratogen, Journal of Biological Chemistry 276:36734-36741, PMID: 11473107.

Phiel CJ and Klein PS (2001) Molecular Targets of Lithium Action, Annual Reviews in Pharmacology and Toxicology 41:789-813, PMID: 11264477.

Phiel CJ, Gabbeta V, Parsons LM, Rothblat D, Harvey RP and McHugh KM (2001) Differential binding of an SRF/NK-2 transcription factor complex in normal versus neoplatic smooth muscle tissues, Journal of Biological Chemistry 276:34637-34650, PMID: 11457859.

Brittingham JW*, Phiel CJ*, Trzyna WT*, Gabbeta V, and McHugh KM (1998) Identification of Distinct Molecular Phenotypes in Cultured Gastrointestinal Smooth Muscle Cells, Gastroenterology 115:605-617, PMID: 9721158 (*Authors contributed equally).

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